Friday, November 5, 2010

Antacid therapy

Antacids are alkaline bases used to neutralize the excess gastric HCl associated with gastritis and peptic ulcers. It acts by two ways (i) by neutralizing of already secreted HCl and (ii) by inactivating of proteolytic enzyme e.g. – pepsin, which acts at lower pH to be said 1-2. As the secretion of gastric HCl is continuous basis so it takes continuous administration of antacid preparations.

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