Friday, November 5, 2010

Criteria of an ideal antacid preparation:

  • The antacid should not be absorbable or cause systemic alkalosis
  • The antacid should not be a laxative or causes constipation
  • The antacid should exert its effect rapidly and over a long period of time
  • The antacid should buffer in the pH 4-6 range
  • The reaction of the antacid with gastric HCl acid should not cause a large evolution of gas
  • The antacid should probably inhibit pepsin

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